Profile

Frank Porreca

Pharmacology

Full Page

Overview

Research

Collaboration(40)

Page 1 of 8

Grants(69)

Identification of a Male-Specific Mechanism of Nociceptor Sensitization Promoting Migraine in Active-Duty Service Members and Veterans
Active·2024·$3K / $300.4K·
External
Co-Investigator (COI)
pain, neuroscience, military, sensitization, migraine
Neuroscience Diversity to Elevate Education and Research Development
Active·2024·$0 / $269.2K·
External
neuroscience, diversity, education, research development
Targeting Prolactin for Prevention of Female-Selective Nociceptor Sensitization for Treatment of Female-Predominant Pain Syndromes
Active·2023·$343.9K / $687.9K·
External
Principal Investigator (PI)
prolactin, nociceptor sensitization, pain syndromes, female-selective, treatment
High School Student NeuroResearch Program (HSNRP)
Active·2023·$21.6K / $269.8K·
External
Multiple Principal Investigator (MPI)
neuroscience, education, research program, high school students, neurology
Brain Circuits of Migraine Pain
Active·2022·$928.9K / $1.9M·
External
Principal Investigator (PI)
neuroscience, pain management, migraine, brain, pain

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Publications(150)

Recent

Opposing Effects on Descending Control of Nociception by µ and κ Opioid Receptors in the Anterior Cingulate Cortex

2023

opioid receptors, nociception, descending control, anterior cingulate cortex, effect

Discovery and characterization of prolactin neutralizing monoclonal antibodies for the treatment of female-prevalent pain disorders

2023

monoclonal antibodies, pain disorders, prolactin, treatment, discovery

Prolactin and pain of endometriosis

2023

prolactin, endometriosis, pain, hormones, chronic disease

Considering Patient Sex in Prescribing CGRP Receptor Antagonists for Short-Term Treatment of Migraine

2023

migraine, cgrp receptor antagonists, patient sex, prescribing, treatment

Preclinical assessment of onabotulinumtoxinA for the treatment of mild traumatic brain injury-related acute and persistent post-traumatic headache

2022

traumatic brain injury, headache, onabotulinumtoxina, preclinical assessment, treatment

Kappa opioid receptor agonists produce sexually dimorphic and prolactin-dependent hyperalgesic priming

2022

pain modulation, sex differences, opioid receptors, prolactin signaling, hyperalgesia

Editorial: Chronic orofacial pain

2022

chronic pain, orofacial pain, editorial, pain management, neurology

Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain

2022

neurobiology, pain management, pharmacology, neuroscience, behavioral research

Conotoxin contulakin-G engages a neurotensin receptor 2/R-type calcium channel Cav2.3) pathway to mediate spinal antinociception

2022

neuroscience, pain management, pharmacology, ion channels, drug discovery

Relief of neuropathic pain by cell-specific manipulation of nucleus accumbens dopamine D1- and D2-receptor-expressing neurons

2022

neuropathic pain, dopamine receptors, cell-specific manipulation, nucleus accumbens, relief

People

Profile

Frank Porreca

Collaboration(40)

Sairam Parthasarathy

Shenfeng Qiu

Marlys Witte

Russell Witte

Todd Vanderah

Grants(69)

Identification of a Male-Specific Mechanism of Nociceptor Sensitization Promoting Migraine in Active-Duty Service Members and Veterans

Neuroscience Diversity to Elevate Education and Research Development

Targeting Prolactin for Prevention of Female-Selective Nociceptor Sensitization for Treatment of Female-Predominant Pain Syndromes

High School Student NeuroResearch Program (HSNRP)

Brain Circuits of Migraine Pain

Publications(150)

Opposing Effects on Descending Control of Nociception by µ and κ Opioid Receptors in the Anterior Cingulate Cortex

Discovery and characterization of prolactin neutralizing monoclonal antibodies for the treatment of female-prevalent pain disorders

Prolactin and pain of endometriosis

Considering Patient Sex in Prescribing CGRP Receptor Antagonists for Short-Term Treatment of Migraine

Preclinical assessment of onabotulinumtoxinA for the treatment of mild traumatic brain injury-related acute and persistent post-traumatic headache

Kappa opioid receptor agonists produce sexually dimorphic and prolactin-dependent hyperalgesic priming

Editorial: Chronic orofacial pain

Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain

Conotoxin contulakin-G engages a neurotensin receptor 2/R-type calcium channel Cav2.3) pathway to mediate spinal antinociception

Relief of neuropathic pain by cell-specific manipulation of nucleus accumbens dopamine D1- and D2-receptor-expressing neurons