Professor, Child Health | Professor, Internal Medicine | Professor, BIO5 Institute | Member of the Graduate Faculty
"Dr. Kalin's research has largely focused on creating a non-toxic small molecule inhibitor compound that can be used to kill cancer cells. In addition, her team has developed tumor-cell-specific nanoparticles that deliver the inhibitor compound directly to cancer cells, blocking specific targeted proteins. Models have shown this approach can prevent tumor progression, metastasis and regrowth. She has also pioneered a method of delivering protons at very high speeds to tumor tissue to kill tumor cells in a way that's more efficient and less toxic to the healthy surrounding tissue. Protecting healthy tissue is especially important when treating cancer in children who are still growing and developing. Dr. Kalin's contributions to the medical and scientific communities are significant. To date, her research has been awarded more than $11.5 million in federal and grant funding. She has served as principal investigator or co-investigator on several R01 studies funded by the National Institutes of Health. She has published more than 70 original peer-reviewed articles and is the recipient of many high-profile awards including the American Cancer Society's Research Scholar and Supplemental Awards, the Cambridge Foundation Award for lung cancer research and the Conquer Cancer Now Award from the Concern Foundation. "