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Jayati Chakrabarti
Associate Scientific Investigator
Cellular & Molecular Medicine
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Research Area
cancer,
organoids,
gastric cancer,
pancreatic cancer,
immunotherapy,
cell signaling,
cushing's disease,
tumor microenvironment,
helicobacter pylori,
organoid models,
injury response,
immune response,
cancer immunotherapy,
targeted therapy,
neuroendocrine,
gastric,
hedgehog signaling,
regeneration,
gastric epithelium,
inflammation,
gene expression,
infection,
immunology,
cell biology,
stem cells
Grants
(1)
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Publications
(109)
Recent
Cabozantinib changes the landscape of the pancreatic tumor microenvironment and improves the efficacy of pembrolizumab
2024
pancreatic cancer,
immunotherapy,
tumor microenvironment,
efficacy
Tu1211 CABOZANTINIB INCREASES THE EFFICACY OF PEMBROLIZUMAB IN HUMAN PANCREATIC DUCTAL ADENOCARCINOMA ORGANOID COCULTURES
2024
cancer immunotherapy,
pancreatic cancer,
combination therapy,
organoid models
Pituitary Neuroendocrine Tumor Organoids Generated from Induced Pluripotent Stem Cells Reveal the Dysregulation of Cell Lineage Differentiation in Cushing’s Disease
2024
neuroendocrine tumor,
stem cells,
cushing's disease,
organoids
166 Development of non-model organoids in animal research: A paradigm shift in in vitro models
2024
organoids,
animal research,
development,
paradigm shift
8773 CD44 Variant Isoforms Expressed Within PAX7/SOX2-Positive Pituitary Neuroendocrine Tumors Attribute to Therapy Resistance and Recurrence of Cushing’s Disease
2024
pituitary tumors,
cushing's disease,
therapy resistance,
neuroendocrine tumors
EXTH-73. TARGETING THE CELL ADHESION CLUSTER OF DIFFERENTIATION 44 TRANSMEMBRANE GLYCOPROTEIN SENSITIZES CRANIOPHARYNGIOMAS TO IMMUNOTHERAPY
2024
immunotherapy,
cancer,
cell adhesion,
transmembrane proteins,
targeted therapy
Cabozantinib changes the tumor microenvironment to increase the efficacy of immunotherapy in refractory metastatic pancreatic ductal adenocarcinoma
2024
immunotherapy,
pancreatic cancer,
tumor microenvironment,
metastatic cancer
Su1202 TARGETING THE CD44 VARIANT ISOFORMS USING A NOVEL CDC-LIKE PROTEIN KINASE INHIBITOR TO IMPROVE THE EFFICACY OF STANDARD-OF-CARE THERAPY FOR PANCREATIC DUCTAL ADENOCARCINOMA
2024
cancer,
targeted therapy,
pancreatic cancer,
treatment efficacy
OR20-05 Generation Of CDH23-mutated Pituitary Neuroendocrine Tumor Organoids From Induced Pluripotent Stem Cells To Model Cushing’s Disease Pathogenesis
2023
pituitary,
neuroendocrine,
stem cells,
cushing's disease
SAT625 The EGF-TBX19-EGFR Positive Feedback LooRegulates The Expression Of The CD44v9/SLC7A11 Antioxidant System Within Corticotroph Pituitary Neuroendocrine Tumors
2023
cancer,
gene regulation,
neuroendocrine tumors,
cell signaling
Collaborations
(15)
Denise Roe
Mutual work: 3 Proposals
Collaboration Details
Baldassarre Stea
Mutual work: 2 Proposals
Collaboration Details
Rachna Shroff
Mutual work: 4 Proposals
Collaboration Details
Megha Padi
Mutual work: 1 Proposal
Collaboration Details
Ritu Pandey
Mutual work: 1 Grant﹒4 Proposals
Collaboration Details
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Courses
(1)
Cell Biology Basics
10+ Collaborators
$284.5K / $2.8M Funding
100+ Publications
