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Tarjani Thaker
Member of the Graduate Faculty | Assistant Professor
College of Medicine - Tucson
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Research Area
cell signaling,
molecular biology,
protein structure,
structural biology,
protein interactions,
cellular signaling,
protein function,
biochemistry,
abc transporter,
drug binding
Grants
(3)
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Publications
(18)
Recent
The N-terminal signature motif on the transporter MCT1 is critical for CD147-mediated trafficking
2024
transporter proteins,
protein trafficking,
cell biology,
molecular biology,
membrane proteins
The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation
2022
protein regulation,
transporter regulation,
phosphorylation,
cellular transport,
structural biology
Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter
2022
drug binding,
abc transporter,
atp-loaded state,
inward-facing,
asymmetric binding
Structures of the active HER2/HER3 receptor complex reveal dynamics at the dimerization interface induced by binding of a single ligand
2021
proteins,
cell signaling,
protein dynamics,
ligand binding
The role of novel COQ8B mutations in glomerulopathy and related kidney defects
2021
genetics,
kidney disease,
mutations,
glomerulopathy,
coq8b
Cryo-EM structure of an elusive pre-transport intermediate of the multidrug ABC transporter BmrCD reveals modes of asymmetric drug binding
2021
cryo-em,
abc transporter,
drug binding,
pre-transport,
asymmetric
Structures of the HER2–HER3–NRG1β complex reveal a dynamic dimer interface
2021
protein interactions,
cancer research,
molecular biology,
cell signaling,
structural biology
A conserved motif in intracellular loo1 stabilizes the outward-facing conformation of TmrAB
2021
protein structure,
membrane transport,
cell biology,
molecular biology,
biochemistry
More than the sum of the parts: Toward full‐length receptor tyrosine kinase structures
2019
protein structure,
cell signaling,
receptor biology,
molecular biology,
biochemistry
Functional role of PGAM5 multimeric assemblies and their polymerization into filaments
2019
protein function,
enzyme regulation,
cell signaling,
structural biology,
polymerization
Collaborations
(4)
Thomas Tomasiak
Mutual work: 4 Proposals﹒2 Grants
Collaboration Details
Martha Bhattacharya
Mutual work: 1 Grant﹒1 Proposal
Collaboration Details
A F M Tariqul Islam
Mutual work: 1 Supervisor
Collaboration Details
Andy Powell
Mutual work: 1 Grant﹒1 Proposal
Collaboration Details
Courses
(3)
Biochemistry
Methods of Physical Biochemistry
Introduction to Biochemical Research
$20K / $851.5K Funding
10+ Publications
