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Paulo Pires
Member of the Graduate Faculty | Assistant Professor, Physiology | Assistant Professor, Surgery
Physiology
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Research Area
hypertension,
alzheimer's disease,
neuroscience,
cerebral arterioles,
vascular biology,
mouse model,
ion channels,
endothelium,
endothelial function,
cerebral artery,
vascular health,
neurodegeneration,
brain injury,
calcium signaling,
cell signaling,
aging,
endothelial dysfunction,
inflammation,
cerebrovascular,
rats,
cardiovascular disease,
obesity,
mineralocorticoid receptor,
smooth muscle cells,
smooth muscle,
vascular physiology,
cerebral blood flow,
neuroprotection,
trpa1 channels,
lymphatic system
Grants
(8)
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Publications
(96)
Recent
Nitro‐oxidation of BKCa mediates neuro‐ and micro‐vascular dysfunction in female 5x‐FAD mice
2024
PNA5, A Novel Mas Receptor Agonist, Improves Neurovascular and Blood-Brain-Barrier Function in a Mouse Model of Vascular Cognitive Impairment and Dementia
2024
neurovascular,
blood-brain barrier,
mas receptor,
vascular cognitive impairment,
dementia
Cervical lymphatic vessel dysfunction induced by amyloid-β and in the 5x-FAD mouse model of Alzheimer’s disease
2024
alzheimer's disease,
lymphatic system,
amyloid-β,
mouse model
Sex‐specific mechanisms of cerebral microvascular BKCa dysfunction in a mouse model of Alzheimer's disease
2024
alzheimer's disease,
mouse model
Basic Science and Pathogenesis
2024
pathogenesis,
basic science,
disease mechanisms,
cellular processes,
medical research
TRP channels in cerebral vascular disorders
2024
ion channels,
cerebrovascular diseases,
neuroscience,
vascular biology,
drug targets
The ebbs and tides of endothelial K+ currents that regulate blood flow
2024
endothelial function,
blood flow regulation,
potassium currents,
vascular physiology
Endothelial KIR2 channel dysfunction in aged cerebral parenchymal arterioles
2023
endothelial function,
aging,
cerebral arterioles,
ion channels,
vascular health
Role of TRPV4 in superficial cervical lymphatic vessel contractile function
2023
lymphatic function,
trpv4 receptor,
cervical lymphatics,
contractile function,
cellular signaling
A novel therapeutic Ang 1-7) analogue improves neurovascular function in mice with vascular contributions to cognitive impairment and dementia
2023
neurovascular function,
cognitive impairment,
dementia,
therapeutic analogue,
vascular contributions
Collaborations
(37)
Helena Morrison
Mutual work: 1 Publication
Collaboration Details
Russell Witte
Mutual work: 6 Proposals﹒6 Publications
Collaboration Details
Marlys Witte
Mutual work: 9 Proposals﹒1 Grant﹒9 Publications
Collaboration Details
Lee Ryan
Mutual work: 2 Proposals﹒1 Grant
Collaboration Details
Geoffrey Gurtner
Mutual work: 2 Proposals
Collaboration Details
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Courses
(3)
Cellular and Molecular Physiology
Physiology for Biomedical Engineering
Human Physiology
30+ Collaborators
$1.8M / $3.2M Funding
7+ Grants
90+ Publications
