Our research groustudies the interface between the immune system and the world around us, on us, or within us. My work seeks to study the complex molecular language that our immune system uses to sense the world. The immune system recognizes microbes pathogens commensals) allergens, mutated genes in cancerous cells neo-antigens) transplanted tissues allo-antigens) and sometimes accidentally recognizes and responds to our own bodies in the setting of autoimmune disease. The goal of my grouis to use genetic and computational tools to discover the rules for this recognition process. Keywords: Immunology, Immuno-Informatics, Infectious Disease, Autoimmunity