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Vance Nielsen
Professor, Anesthesiology | Member of the Graduate Faculty
Anesthesiology
Map Page
Research Area
coagulation,
carbon monoxide,
snake venom,
venom,
fibrinolysis,
toxicology,
hemostasis,
iron,
hematology,
plasma,
blood coagulation,
hemeoxygenase-1,
hypercoagulability,
oncology,
biochemistry,
plasmatic coagulation,
cardiopulmonary bypass,
heme modulation,
medical devices,
biomedical research,
iron metabolism,
heme oxygenase,
thrombin activity,
snake venoms,
snake,
fibrinogen,
fibrinogenase,
fibrinogenolytic activity,
inhibition,
anticoagulant
Grants
(4)
Deciphering Tranexamic Acid's Enigma: Revolutionizing Surgical Hemostasis & Thrombosis Prevention
Active
·
2024
·
$0 / $72.4K
·
External
Key Personnel (KP)
tranexamic acid,
surgical hemostasis,
thrombosis prevention,
revolutionizing,
deciphering
Verification of the Formulation of Rejuvesol: Assessment of Composition, Sterility and Particle-Free Packaging
Active
·
2024
·
$62.8K
·
External
Principal Investigator (PI)
pharmaceuticals,
quality control,
packaging,
sterility,
composition analysis
Ruthenium-Based Antivenom Development
2022
·
$100K
·
External
Principal Investigator (PI)
snake venom,
medical treatment,
ruthenium complexes,
toxin neutralization,
antivenom innovation
Hemolysis-Mediated Hypercoagulability I Hemodialysis Patients: Role of Hemeoxygenase - 1
2013
·
$5.5K / $9.1K
·
External
Co-Investigator (COI)
hemolysis,
hypercoagulability,
hemodialysis,
heme oxygenase,
role
Publications
(205)
Recent
Phosphate-Buffered Saline and Dimethyl Sulfoxide Enhance the Antivenom Action of Ruthenium Chloride against Crotalus atrox Venom in Human Plasma—A Preliminary Report
2024
antivenom action,
saline solution,
venom,
ruthenium chloride,
plasma
Ruthenium Antivenom Inhibits the Defibrinogenating Activity of Crotalus adamanteus Venom in Rabbits
2024
antivenom,
venom,
defibrinogenating,
animal model,
ruthenium
The Gilded Clot: Review of Metal-Modulated Platelet Activation, Coagulation, and Fibrinolysis
2023
platelet activation,
coagulation,
fibrinolysis,
metal modulation,
review
Novel Toxicodynamic Model of Subcutaneous Envenomation to Characterize Snake Venom Coagulopathies and Assess the Efficacy of Site-Directed Inorganic Antivenoms
2023
toxicodynamics,
envenomation,
snake venom,
coagulopathies,
antivenoms
Searching for an Alternate Anticoagulant for Cardiopulmonary Bypass: Does Two Plus Two Equal Two?
2022
anticoagulant,
cardiopulmonary bypass,
drug discovery,
coagulation,
medical research
A Case Report of Severe Factor XI Deficiency during Cardiac Surgery: Less Can Be More
2022
factor xi deficiency,
cardiac surgery,
case report,
severe,
hemostasis
Review of the Mechanisms of Snake Venom Induced Pain: It’s All about Location, Location, Location
2022
snake venom,
pain mechanisms,
location,
review article,
pain research
Ruthenium chloride inhibits the anticoagulant activity of the phospholipase A-dependent neurotoxin of Mojave rattlesnake Type A venom
2021
biochemistry,
snake venom,
toxin inhibition,
anticoagulant activity,
ruthenium chloride
Modulation of Diverse Procoagulant Venom Activities by Combinations of Platinoid Compounds.
2021
venom,
modulation,
platinoid compounds,
procoagulant,
activities
Thrombocytosis and neutrophilia associated with oxygenator failure and protamine reaction after cardiopulmonary bypass: a case report and literature review
2021
thrombocytosis,
neutrophilia,
cardiopulmonary bypass,
oxygenator failure,
protamine reaction
Collaborations
(5)
Paul Langlais
Mutual work: 1 Publication
Collaboration Details
Martin Weinand
Mutual work: 1 Publication
Collaboration Details
Amy Sussman
Mutual work: 1 Publication
Collaboration Details
James Warneke
Mutual work: 2 Publications
Collaboration Details
Marlon Guerrero
Mutual work: 1 Publication
Collaboration Details
News
(5)
Major Advance in Snakebite Treatment
2017
UA's Top Stories: Robbins, de Kooning and More
2017
UA Funds Early-Stage Inventions for Market Readiness
2017
UA Expert Has Safety Tips for Snakebite Season
2016
New Snakebite Treatment Under Development at UA
2016
Techs/Patents
(7)
Formulations to Inhibit Hemotoxic Venoms
2020
·
Technology
Compositions And Methods For Treating And Preventing Venom Related Poisoning
2020
·
Patent
Compositions And Methods For Treating And Preventing Venom Related Poisoning
2019
·
Patent
Methods for Diagnosing Iron-Related Pathologies
2018
·
Patent
Method to Prevent Venom Induced Coagulopathy
2015
·
Technology
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4+ Collaborators
$168.2K / $244.3K Funding
200+ Publications
6+ Tech/Patents
4+ News
