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Stephen Wright
Professor Emeritus
Physiology
Map Page
Research Area
drug transport,
drug interactions,
pharmacokinetics,
pharmacology,
nucleoside transporters,
molecular biology,
transporter proteins,
cellular transport,
biochemistry,
organic cation,
renal function
Grants
(11)
Southwest Environmental Health Sciences Center
Active
·
2023
·
$76.8K / $3.1M
·
External
Co-Investigator (COI)
environmental health,
biomedical research,
environmental sciences,
public health,
epidemiology
Renal Disposition in NASH
Active
·
2019
·
$363.8K / $2.4M
·
External
Co-Investigator (COI)
renal disease,
nash,
liver disease,
metabolic syndrome,
inflammation
MegaTrans - Human Transporter Machine Learning Models
2019
·
$95.5K
·
External
Principal Investigator (PI)
machine learning,
transportation,
human,
models,
technology
Improving In Vitro-In Vivo Extrapolation for Renal Cationic Drug Transport
2018
·
$614K
·
External
Principal Investigator (PI)
renal transport,
pharmacokinetics,
drug transport,
in vitro-in vivo extrapolation,
renal function
Circumventing the Blood-Testis Barrier
2017
·
$390K / $1.2M
·
External
Co-Investigator (COI)
reproduction,
barrier,
blood,
testis,
health
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Publications
(48)
Recent
Testicular disposition of clofarabine in rats is dependent on equilibrative nucleoside transporters
2021
pharmacokinetics,
nucleoside transporters,
clofarabine,
testicular disposition,
rat model
Cationic Compounds with SARS-CoV-2 Antiviral Activity and Their Interaction with Organic Cation Transporter/Multidrug and Toxin Extruder Secretory Transporters
2021
antiviral,
cationic compounds,
drug interaction,
transporters,
sars-cov-2
Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1
2021
drug interactions,
computational approaches,
human equilibrative nucleoside transporter 1,
drug prediction,
bioinformatics
Remdesivir and EIDD-1931 Interact with Human Equilibrative Nucleoside Transporters 1 and 2: Implications for Reaching SARS-CoV-2 Viral Sanctuary Sites
2021
antiviral drugs,
nucleoside transporters,
sars-cov-2,
drug interactions,
viral sanctuary sites
Generation of a hTERT-Immortalized Human Sertoli Cell Model to Study Transporter Dynamics at the Blood-Testis Barrier
2020
cell models,
barrier function,
transporter dynamics,
sertoli cells,
cell culture
Predicting Drug Interactions with Human Equilibrative Nucleoside Transporters 1 and 2 Using Functional Knockout Cell Lines and Bayesian Modeling
2020
drug interactions,
nucleoside transporters,
functional knockout,
bayesian modeling,
cell lines
Nucleoside Reverse Transcriptase Inhibitor Interaction with Human Equilibrative Nucleoside Transporters 1 and 2
2020
drug interaction,
nucleoside transporters,
antiviral therapy,
hiv treatment,
pharmacokinetics
Molecular and cellular physiology of organic cation transporter 2
2019
molecular physiology,
cellular physiology,
organic cation transporter,
molecular transport,
cellular transport
Kinetic basis of metformin-MPP interactions with organic cation transporter OCT2
2019
drug transport,
metformin,
pharmacokinetics,
drug interactions,
transporter proteins
Assessment of Substrate-Dependent Ligand Interactions at the Organic Cation Transporter OCT2 Using Six Model Substrates
2018
pharmacology,
drug transport,
ligand interactions,
substrate specificity,
transporter proteins
Collaborations
(15)
Walter Klimecki
Mutual work: 2 Proposals
Collaboration Details
Nathan Cherrington
Mutual work: 25 Proposals﹒12 Publications﹒4 Grants
Collaboration Details
Jason Wertheim
Mutual work: 4 Proposals
Collaboration Details
William Montfort
Mutual work: 1 Proposal
Collaboration Details
Dean Billheimer
Mutual work: 2 Grants﹒17 Proposals
Collaboration Details
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News
(1)
UA Community Gives Thanks to Faculty
2013
Courses
(4)
Research Methods in Physiology
Integrative Cellular Physiology
Human Anatomy and Physiology I
Cellular and Molecular Physiology
10+ Collaborators
$9.1M / $16.7M Funding
10+ Grants
40+ Publications