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Kevin Gaffney
Assistant Research Professor, Pharmacology - (Research Series Track)
Pharmacology
Map Page
Research Area
drug development,
medical research,
rasrx1902,
treatment,
chemotherapy,
colorectal cancer,
small molecule inhibitors,
interleukin-8 pathway,
cxcr2 inhibitors,
molecular biology
Grants
(5)
Biomarker Development for the Evaluation of Mas Agonist, RASRx1902, in Amyotrophic Lateral Sclerosis
Active
·
2022
·
$152.1K / $1.5M
·
External
Co-Investigator (COI)
biomarker development,
mas agonist,
rasrx1902,
amyotrophic lateral sclerosis,
evaluation
IND Enabling Studies for RASRx 1902, a Novel Mas Receptor Agonist, for Treatment of Cognitive Impairment in Patients at Risk for Alzheimer's Disease
Active
·
2020
·
$1.5M / $6.5M
·
External
Co-Investigator (COI)
alzheimer's disease,
cognitive impairment,
mas receptor agonist,
ind enabling studies,
rasrx1902
Therapeutic Idea for the Treatment of ALS with RASRx1902
2019
·
$89.4K / $893.6K
·
External
Co-Investigator (COI)
als treatment,
therapeutic,
rasrx1902,
neurodegenerative diseases,
drug development
Arizona Alzheimer's Consortium Match Projects
2019
·
$18K / $300K
·
External
Co-Investigator (COI)
alzheimer's research,
consortium collaboration,
arizona initiatives,
medical research,
dementia studies
Arizona Alzheimer's Consortium Match Projects
2018
·
$15K / $300K
·
External
Co-Investigator (COI)
alzheimer's,
consortium,
arizona,
match,
projects
Publications
(19)
Recent
Mitigation of cognitive decline and brain pathology after transaortic constriction by Mas agonists
2021
cognitive decline,
brain pathology,
mas agonists,
transaortic constriction,
mitigation
P1‐085: MAS AGONISTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASE
2019
neurodegenerative disease,
agonists,
treatment,
mas,
research
Improving the innate immune response in diabetes by modifying the renin angiotensin system
2019
diabetes,
innate immune,
renin-angiotensin system,
immune response,
modification
Development of angiotensin II 1-7) analog as an oral therapeutic for the treatment of chemotherapy-induced myelosuppression
2018
chemotherapy-induced myelosuppression,
angiotensin ii 1-7 analog,
oral therapeutic,
development,
treatment
Methods, compounds, and compositions for the treatment of musculoskeletal diseases
2018
musculoskeletal diseases,
treatment methods,
compounds,
compositions,
medical research
A(1-7) reduces pathologies associated with SLE in MRL-lpr mice
2018
autoimmunity,
immunology,
mice models,
pathology,
drug development
Methods, compounds, and compositions for the treatment of angiotensin-related diseases
2017
drug development,
angiotensin,
therapeutic compounds,
disease treatment,
medical research
Evaluation of MMX1902 as an Oral Treatment for Duchenne Muscular Dystrophy
2016
drug efficacy,
duchenne muscular dystrophy,
clinical trial,
oral administration,
drug development
Molecular characterization of the boron adducts of the proteasome inhibitor bortezomib with epigallocatechin-3-gallate and related polyphenols.
2015
molecular biology,
chemistry,
pharmacology,
biochemistry,
polyphenols
Abstract 1811: Evaluation of anti-CXCR2 small molecule inhibitors as novel chemotherapy targeting the Interleukin-8 pathway in colorectal cancer
2014
chemotherapy,
colorectal cancer,
small molecule inhibitors,
interleukin-8 pathway,
cxcr2 inhibitors
Collaborations
(11)
Bonnie LaFleur
Mutual work: 2 Grants﹒2 Proposals
Collaboration Details
Todd Vanderah
Mutual work: 1 Proposal
Collaboration Details
Elsa Reyes Reyes
Mutual work: 1 Grant
Collaboration Details
Roberta Brinton
Mutual work: 2 Grants﹒6 Proposals
Collaboration Details
Theodore Trouard
Mutual work: 2 Proposals﹒1 Grant
Collaboration Details
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News
(1)
Developing a Diverse Workforce To End the Alzheimer’s Epidemic
2019
Techs/Patents
(2)
Methods For Treating Or Limiting Development Of Cardiovascular Disease-Related Neurological Disorders
2023
·
Patent
Use of an Individual's Own Neural Network-Based Text To Speech Voice in Patients without Vocal Capacity Due to ALS and Other Conditions
2019
·
Technology
10+ Collaborators
$1.8M / $9.5M Funding
4+ Grants
10+ Publications