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Jing Wei
Assistant Scientific Investigator, Basic Medical Sciences
COM Phx Basic Medical Sci
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Research Area
neuroscience,
alzheimer's disease,
molecular biology,
stress,
prefrontal cortex,
genetics,
psychiatry,
neurological disorders,
synaptic function,
plasticity,
cortical circuits,
cortical circuit,
mouse model
Grants
(4)
Biological Function and Regulation of PRMT9 in Synapse Development
Active
·
2024
·
$6.4K / $128.9K
·
External
Key Personnel (KP)
synapse development,
prmt9 regulation,
biological function,
neuronal signaling,
protein methylation
Neuronal and Circuit-Specific Maladaptations Contributing to Cocaine Addiction
Active
·
2023
·
$25K / $500K
·
External
Co-Investigator (COI)
neuroscience,
addiction,
circuitry,
maladaptations,
neurons
Molecular and Circuit Mechanisms Underlying Cocaine Addiction
Active
·
2023
·
$25K / $124.8K
·
External
Key Personnel (KP)
neurobiology,
addiction,
molecular biology,
psychiatry,
behavioral neuroscience
Environmental Regulation of Cortical Gene Expression and Circuit Function
Active
·
2019
·
$0 / $1.6M
·
External
Co-Investigator (COI)
gene expression,
environmental regulation,
cortical circuit,
gene regulation,
neuroscience
Publications
(37)
Recent
Left frontal eye field encodes sound locations during passive listening
2023
neuroscience,
auditory perception,
neural encoding,
cognitive neuroscience,
spatial localization
Disrupted maturation of prefrontal layer 5 neuronal circuits in an Alzheimer’s mouse model of amyloid deposition
2023
alzheimer's disease,
neuronal circuits,
prefrontal cortex,
mouse model,
amyloid deposition
Reduced HGF/MET Signaling May Contribute to the Synaptic Pathology in an Alzheimer's Disease Mouse Model
2022
alzheimer's disease,
synaptic pathology,
hgf/met signaling,
mouse model,
reduced signaling
Disrupted timing of MET signaling derails the developmental maturation of cortical circuits and leads to altered behavior in mice
2022
developmental timing,
cortical circuits,
met signaling,
behavioral changes,
neurodevelopmental disorders
Early impairment of cortical circuit plasticity and connectivity in the 5XFAD Alzheimer’s disease mouse model
2022
alzheimer's disease,
cortical circuit,
plasticity,
connectivity,
mouse model
Early Disruption of Synaptic Function, Impairment of Plasticity, and Decreased of Cortical Circuit Connectivity in an Alzheimer’S Mouse Model of Amyloid Deposition
2021
alzheimer's,
synaptic function,
plasticity,
cortical circuit,
amyloid deposition
Time-delimited signaling of MET receptor tyrosine kinase regulates cortical circuit development and critical period plasticity
2021
neurodevelopment,
neuroplasticity,
signaling,
cortical circuits,
met receptor
Conditional knockout of MET receptor tyrosine kinase in cortical excitatory neurons leads to enhanced learning and memory in young adult mice but early cognitive decline in …
2021
neuroscience,
cognitive decline,
genetics,
learning and memory,
neurological disorders
DNA methyltransferase 3A is involved in the sustained effects of chronic stress on synaptic functions and behaviors
2021
dna methylation,
chronic stress,
synaptic functions,
behavior,
neuroscience
Depletion of microglia in developing cortical circuits reveals its critical role in glutamatergic synapse development, functional connectivity, and critical period plasticity
2020
microglia,
synapse development,
functional connectivity,
plasticity,
cortical circuits
Collaborations
(14)
Shenfeng Qiu
Mutual work: 4 Grants﹒27 Proposals﹒3 Publications﹒1 Supervisor
Collaboration Details
Jonathan Lifshitz
Mutual work: 2 Proposals
Collaboration Details
Frank Porreca
Mutual work: 1 Proposal
Collaboration Details
Chengcheng Hu
Mutual work: 2 Proposals﹒1 Grant
Collaboration Details
Fei Yin
Mutual work: 1 Proposal
Collaboration Details
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10+ Collaborators
$56.4K / $2.3M Funding
30+ Publications