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The University of Arizona
1230 N Cherry Ave
Tucson, AZ USA 85721
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rii-kmap@arizona.edu
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© 2024 The Arizona Board of Regents on behalf of The University of Arizona.

Picture of Jean Wilson

Jean Wilson

Professor, BIO5 Institute | Professor, Cancer Biology - GIDP | Member of the Graduate Faculty | Professor, Neuroscience - GIDP | Professor, Cellular and Molecular Medicine | Director, Willed Body Program

Cellular & Molecular Medicine

Research Area

cell biology, cell signaling, protein regulation, viral infection, membrane trafficking, endocytosis, intestinal health, protein interactions, molecular regulation, regulation

Modulation of Colonocyte Barrier Function and Signaling by Cytomegalovirus Infection
Active·2024·$217.2K / $543.1K·
External
Principal Investigator (PI)
viral infection, intestinal barrier, cell signaling, colon health, immune response
Infection and Inflammation as Drivers of Aging (IIDA) Predoctoral Training Program
Active·2024·$0 / $292.3K·
External
aging, infection, inflammation, pre-doctoral, training
Autophagy and LC3-Associated Phagocytosis in Intestinal Epithelial Cells.
Active·2022·$1.3M / $1.3M·
External
Principal Investigator (PI)
autophagy, phagocytosis, intestinal epithelial cells, lc3, cell biology
(SRA) Non-Canonical Roles of NHE3 in the Colonic Epithelium
Active·2021·$69.5K / $347.4K·
External
Co-Investigator (COI)
intestinal health, epithelial transport, membrane protein, gastrointestinal physiology, cellular signaling
CMV Control of Host Membrane Trafficking
2018·$667.7K / $2.1M·
External
Multiple Principal Investigator (MPI)
health disparities, viral infection, cell biology, immunology, diversity in research

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Recent

Cell type-specific biogenesis of novel vesicles containing viral products in human cytomegalovirus infection

2021

viral infection, cell biogenesis, vesicle formation, cellular response, viral product trafficking

Proliferation in the developing intestine is regulated by the endosomal protein Endotubin

2021

intestinal development, endosomal regulation, cell proliferation, protein regulation, developmental biology

Rab22a regulates the establishment of epithelial polarity

2020

cellular polarity, rab gtpases, cell biology, intracellular trafficking, epithelial cells

Intestinal Epithelial Expression of MHCII Determines Severity of Chemical, T-Cell-Induced, and Infectious Colitis in Mice

2020

intestinal, colitis, mhcii, infectious, t-cell

Loss of Myosin Vb promotes apical bulk endocytosis in neonatal enterocytes

2019

cell biology, endocytosis, myosin vb, neonatal enterocytes, apical membrane

Rapid Downregulation of DAB2 by Toll-Like Receptor Activation Contributes to a Pro-Inflammatory Switch in Activated Dendritic Cells

2019

immunology, cell signaling, inflammation, gene regulation, dendritic cells

Virus Control of Trafficking from Sorting Endosomes

2018

virus-host interactions, endocytic pathways, intracellular transport, viral infection, cellular trafficking

The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation

2017

cell biology, endocytosis, protein trafficking, cell differentiation, gastrointestinal biology

Arf6 and Rab22 mediate T cell conjugate formation by regulating clathrin-independent endosomal membrane trafficking

2017

t cell conjugate formation, endosomal membrane trafficking, arf6, rab22, clathrin-independent

Rabs set the stage for polarity

2017

cell polarity, protein regulation, membrane trafficking, cytoskeleton dynamics, molecular transport

David Besselsen
Julie Ledford
Fayez Ghishan
Jacobus Barnard
Paul Langlais

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Celebrating Women in Medicine Month with Felicia Goodrum
2018

Scientific Grantsmanship
Cell Biology of Disease
Principles of Cell Biology
Scientific Writing
Scientific Writing and Research Integrity

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10+ Collaborators

$6.6M / $10.4M Funding

20+ Publications