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Eugene Mash
Professor, Chemistry and Biochemistry-Sci | Member of the Graduate Faculty
Chemistry & Biochemistry - Sci
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Research Area
magnetic resonance imaging,
drug development,
environmental chemistry,
organic chemistry,
cancer,
chemical engineering,
contrast agents,
fluorescence probes,
competitive binding,
time-resolved
Grants
(10)
(LTW) Novel Therapeutic Delivery System for Pediatric IBD
2022
·
$65K / $130K
·
External
Co-Investigator (COI)
pediatric ibd,
therapeutic delivery,
novel system,
pediatric health,
drug delivery
The Development of a Solvent Free Process to Prepare DNAN
2017
·
$28.9K
·
External
Principal Investigator (PI)
green chemistry,
chemical engineering,
eco-friendly synthesis,
materials science,
environmental chemistry
UNS: Oligomers Derived from Emerging Nitroaromatic Pollutants in Anaerobic Environments: Mechanisms, Fate and Toxicity
2015
·
$99K / $330K
·
External
Co-Investigator (COI)
pollutant degradation,
anaerobic environments,
toxicity,
nitroaromatic compounds,
oligomer formation
Development of New Liquid Crystalline Polyamides with Bicyclo[8.8.8] Hexacosane Flexible Segments
2015
·
$55K / $110K
·
External
Principal Investigator (PI)
polymer synthesis,
liquid crystals,
polyamide materials,
flexible segments,
material development
Targeting Pancreatic Cancer
2009
·
$217.9K / $871.4K
·
External
Co-Investigator (COI)
pancreatic cancer,
cancer therapy,
targeted therapy,
biomarker identification,
precision medicine
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Publications
(118)
Recent
Coupling reactions between reduced intermediates of insensitive munitions compound analog 4-nitroanisole.
2019
organic chemistry,
chemical engineering,
environmental chemistry,
catalysis,
munitions
Magnetic resonance imaging of RRx-001 pharmacodynamics in preclinical tumors
2017
magnetic resonance imaging,
pharmacodynamics,
preclinical tumors,
rrx-001,
research
Solvent-free nitration of electron-rich arenes
2017
organic chemistry,
chemical engineering,
green chemistry,
synthesis,
aromatic compounds
Magnetic Resonance Imaging Identifies Differential Response to Pro-Oxidant Chemotherapy in a Xenograft Model
2016
chemotherapy,
magnetic resonance imaging,
pro-oxidant,
xenograft model,
differential response
Synthesis and bioactivity of MSH4 oligomers prepared by an A(2) B-2 strategy
2015
oligomer synthesis,
bioactivity,
msh4,
peptide conjugation,
a(2) b-2 strategy
Linear scaffolds for multivalent targeting of melanocortin receptors
2015
peptide chemistry,
drug development,
receptor targeting,
multivalency,
scaffold design
Development of a time-resolved fluorescence probe for evaluation of competitive binding to the cholecystokinin 2 receptor
2015
fluorescence probes,
receptor binding,
time-resolved,
cholecystokinin 2,
competitive binding
IMPROVED SYNTHESIS OF 10-2-ALKYLAMINO-2-OXOETHYL)1,4,7,10-TETRAAZACYCLODODECANE-1,4,7-TRIACETIC ACID DERIVATIVES BEARING ACID-SENSITIVE LINKERS
2014
chemistry,
organic synthesis,
drug development,
bioconjugation,
medicinal chemistry
pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase PTPN1)
2014
cancer,
protein phosphorylation,
curcumin,
ptpn1,
colon
Crystal Engineering with 1,4-Piperazine-2,5-diones
2014
crystal engineering,
organic chemistry,
molecular design,
material science,
drug development
Collaborations
(28)
H-H. Sherry Chow
Mutual work: 5 Proposals
Collaboration Details
Cynthia Thomson
Mutual work: 4 Proposals
Collaboration Details
Nirav Merchant
Mutual work: 1 Proposal
Collaboration Details
Denise Roe
Mutual work: 4 Proposals
Collaboration Details
Jefferey Burgess
Mutual work: 1 Proposal
Collaboration Details
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News
(3)
'Molecular Truck' Could Deliver New Treatment
2015
UA Discovery Shows Curcumin Blocks the Metastasis of Colon Cancer by a Novel Mechanism
2014
Couple's Gift Brings Nobel Laureate to UA
2008
Courses
(6)
Lectures in Organic Chemistry
Synthetic and Mechanistic Organic Chemistry
Biochemistry
Advanced Organic Synthesis
Organic Structural Analysis Laboratory
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Techs/Patents
(24)
Scalable Synthesis for Commercial Production of Carbohydrate-Based Molecular Scaffold Compounds for Direct Delivery of Drugs or Nutritional Supplements to the GI Tract
2021
·
Technology
Method and Compositions for Orally Administered Contrast Agents for MR Imaging
2021
·
Patent
Design and Synthesis of Pro-Drugs for Selective, Oral Delivery to the Gastrointestinal Tract
2020
·
Technology
Nitration of Aromatic Compounds
2020
·
Patent
Novel 5-Fluorouracil Prodrug For Colorectal Cancer Therapy
2018
·
Technology
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20+ Collaborators
$1.2M / $11.8M Funding
9+ Grants
110+ Publications
5+ Courses
20+ Tech/Patents
