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Picture of Matthew Cordes

Matthew Cordes

Associate Professor, BIO5 Institute | Associate Professor, Chemistry and Biochemistry-Sci | Member of the Graduate Faculty

Chemistry & Biochemistry - Sci

Research Area

protein evolution, bioinformatics, molecular biology, phospholipase d, structural biology, protein structure, spider toxins, protein folding, evolutionary biology, genetic variation

MRI: Acquisition of a State-of-the-Art Analytical Ultracentrifuge (AUC) For Biomedical and Materials Research
2020·$0 / $342.9K·
External
Co-Investigator (COI)
mri, biomedical, materials, analytical ultracentrifuge, acquisition
Collaborative Research: Head Group Preference in Recluse Spider Phospholipase D Toxins
2018·$405K·
External
Principal Investigator (PI)
spider toxins, phospholipase d, collaborative research, head group preference, recluse spider
The Conversion of Noncoding Sequences Into Proteins
2013·$417.7K / $835.3K·
External
Principal Investigator (PI)
genetics, protein synthesis, molecular biology, bioinformatics, biotechnology
Conformational Switching in Proteins
2008·$1.3M·
External
Principal Investigator (PI)
protein structure, molecular dynamics, biochemistry, protein folding, structural biology
CAREER: The Functional Evolution of Sequence-Specific DNA-Binding Proteins
2007·$697.5K·
External
Principal Investigator (PI)
protein evolution, dna binding, functional evolution, sequence-specific proteins, career development

Recent

Studying protein fold evolution with hybrids of differently folded homologs

2015

protein evolution, protein folding, hybrid proteins, homologs, evolutionary biology

Spider, bacterial and fungal phospholipase D toxins make cyclic phosphate products

2015

toxin, phospholipase, bacteria, fungus, cyclic phosphate

The Recent De Novo Origin of Protein C-Termini

2015

protein evolution, molecular biology, bioinformatics, evolutionary biology, genomics

Variable Substrate Preference Among Phospholipase D Toxins From Sicariid Spiders

2015

toxin preference, substrate specificity, phospholipase d, spider toxins, substrate preference

A polymetamorphic protein

2013

protein structure, metamorphism, biomolecular function, bioinformatics, molecular biology

Phospholipase D toxins of brown spider venom convert lysophosphatidylcholine and sphingomyelin to cyclic phosphates

2013

spider venom toxins, phospholipase d, lysophosphatidylcholine, sphingomyelin, cyclic phosphates

A role for indels in the evolution of Cro protein folds

2013

protein evolution, structural biology, genetic variation, molecular evolution, mutation dynamics

The porous borders of the protein world

2012

Evolutionary bridges to new protein folds: design of C-terminal Cro protein chameleon sequences

2011

Determinants of gas-phase disassembly behavior in homodimeric protein complexes with related yet divergent structures

2011

John Pollard
Michael Marty
Joanna Masel
Christopher Jones
Nancy Horton

Page 1 of 2

Birth of a New Protein: How Evolution Does More Than Tinker
2017
Spider Venom Reveals New Secret
2013
BIO5 Institute Funds Eight Collaborative Pilot Grants
2012
The Age of Biology is Here
2008
Researchers Tackling Unsolved Questions About Protein Structures
2008

Page 1 of 2

Biological Structure 2
Introduction to Biochemical Research
Biochemistry
Biological Structure I
Nucleic Acids, Metabolism, and Signaling

5+ Collaborators

$2.8M / $3.5M Funding

30+ Publications