Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide that belongs to the vasoactive intestinal peptide (VIP) family. It is involved in various physiological processes such as neurotransmission, hormone secretion, and cell differentiation. Research in the area of PACAP focuses on determining its role in various diseases and conditions, such as neurodegenerative disorders, stress-related disorders, and inflammatory diseases. Additionally, researchers are exploring the potential therapeutic applications of PACAP in treating these conditions. Studies have also shown that PACAP has neuroprotective and anti-inflammatory effects, making it a promising target for drug development.