Keratinocytes are the predominant cell type found in the epidermis, the outermost layer of the skin. They are responsible for producing and maintaining the protein keratin, which provides strength and protection to the skin. Keratinocytes play a crucial role in the barrier function of the skin and are involved in processes such as wound healing, immune responses, and skin pigmentation. Research in this area often focuses on understanding the molecular mechanisms regulating keratinocyte function, as well as how these cells contribute to skin diseases such as psoriasis, eczema, and skin cancer. Additionally, keratinocytes are used in laboratory studies and tissue engineering to develop novel therapies for skin disorders.