Centromere research focuses on understanding the structure, function, and regulation of the centromere, a specialized region of a chromosome that plays a critical role in ensuring proper chromosome segregation during cell division. The centromere is essential for the attachment of spindle fibers and the proper alignment of chromosomes during mitosis and meiosis. Research in this area aims to elucidate the molecular mechanisms that govern centromere function, identify the proteins and DNA sequences involved in centromere formation, and explore the role of centromeres in genome stability and disease. Studying centromeres can provide insights into fundamental aspects of cell biology and can lead to a better understanding of human health and disease.