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Picture of Georg Wondrak

Georg Wondrak

Director, Graduate Studies | Professor, Pharmacology and Toxicology | Professorship, R Ken and Donna Coit | Professor, Cancer Biology - GIDP | Member of the Graduate Faculty

Pharmacology and Toxicology

Collaboration(29)

Bonnie LaFleur
Denise Roe
Baldassarre Stea
Rachna Shroff
Karen Hastings

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Grants(15)

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Publications(73)

Recent

Sensitivity of coronaviruses to terrestrial UV light

2021

virology, uv light, public health, environmental science, epidemiology

The sunless tanning agent dihydroxyacetone induces stress response gene expression and signaling in cultured human keratinocytes and reconstructed epidermis

2020

skin aging, cellular stress, tanning products, gene expression, skin physiology

The Endogenous Tryptophan-derived Photoproduct 6-formylindolo[3,2-b]carbazole FICZ) is a Nanomolar Photosensitizer that Can be Harnessed for the Photodynamic Elimination of Skin Cancer Cells in Vitro and in Vivo

2020

photodynamic therapy, skin cancer, tryptophan, photosensitizer, in vitro

Genetic Target Modulation Employing CRISPR/Cas9 Identifies Glyoxalase 1 as a Novel Molecular Determinant of Invasion and Metastasis in A375 Human Malignant Melanoma Cells In Vitro and In Vivo

2020

genetic target modulation, crispr/cas9, malignant melanoma, invasion and metastasis, glyoxalase 1

Activation of NRF2 by topical apocarotenoid treatment mitigates radiation-induced dermatitis

2020

nrf2 activation, topical treatment, radiation-induced dermatitis, apocarotenoid, skin health

Genomic GLO1 deletion modulates TXNIP expression, glucose metabolism, and redox homeostasis while accelerating human A375 malignant melanoma tumor growth

2020

genomics, glucose metabolism, redox homeostasis, tumor growth, gene deletion

Sun sensitivity and sun protective behaviors during sun exposure among indoor office workers in the American Midwest

2018

sun protection, office workers, sun exposure, sensitivity, behavior

Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy

2018

parkinson's disease, mitochondrial function, redox homeostasis, autophagy, skin fibroblasts

Pharmacological TLR4 Antagonism Using Topical Resatorvid Blocks Solar UV-Induced Skin Tumorigenesis in SKH-1 Mice

2018

pharmacology, skin cancer, uv radiation, tlr4 antagonism, topical treatment

Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin

2018

photodamage, hair graying, skin protection, nrf2, bixin