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Picture of Joanna Masel

Joanna Masel

Professor, Applied Mathematics - GIDP | Professor, Statistics-GIDP | Professor, Psychology | Professor, BIO5 Institute | Member of the Graduate Faculty | Professor, Ecology and Evolutionary Biology | Professor, Genetics - GIDP

Ecology & Evolutionary Biology

Collaboration(16)

Dante Lauretta
Ross Buchan
Michael Marty
Lisa Elfring
George Sutphin

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Grants(13)

Improving, Validating, and Interpreting Amino Acid Substitution Models
Active·2024·$697.5K·
External
Principal Investigator (PI)
bioinformatics, protein evolution, genetics, molecular biology, statistical modeling
Amino Acid Frequencies in Ancient Life
Active·2023·$150K / $50K·
External
Principal Investigator (PI)
paleogenetics, evolution, biochemistry, origins of life, ancient dna
What Life Wants: Exploring the Natural Selection of Elements
Active·2022·$63.4K·
External
Principal Investigator (PI)
evolution, biochemistry, dna, ecology, chemistry
Universal Principles of Evolutionary Adaptation
Active·2021·$249.4K·
External
Principal Investigator (PI)
evolutionary adaptation, universal principles, biology, natural selection, genetic variation
Does an Evolutionary Ratchet of Complexity Rescue Us from Mutation Load?
2020·$564.3K·
External
Principal Investigator (PI)
evolutionary genetics, mutation load, evolutionary biology, complexity theory, genetic rescue

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Publications(94)

Recent

Reconstructing the properties of ancient proteomes in the light of differential loss

2024

proteomics, ancient, evolution, biology

Background Selection From Unlinked Sites Causes Nonindependent Evolution of Deleterious Mutations

2024

genetic evolution, natural selection, population genetics, molecular evolution, mutation accumulation

Order of amino acid recruitment into the genetic code resolved by Last Universal Common Ancestor’s protein domains

2024

genetic code, amino acid recruitment, protein domains, last universal common ancestor, evolutionary biology

Enhanced testing can substantially improve defence against several types of respiratory virus pandemic

2024

pandemic defense, respiratory virus, enhanced testing, public health, infectious diseases

Why there are so many definitions of fitness in models

2024

evolutionary biology, mathematical modeling, population genetics, ecological dynamics, evolutionary ecology

Human deleterious mutation rate implies high fitness variance, with declining mean fitness compensated by rarer beneficial mutations of larger effect

2023

mutation rate, fitness variance, beneficial mutations, mean fitness, deleterious mutation

Optimal targeting of interventions uses estimated risk of infectiousness to control a pandemic with minimal collateral damage

2023

infectiousness, pandemic control, intervention targeting, risk estimation, collateral damage

Differential retention of Pfam domains contributes to long-term evolutionary trends

2023

The Interaction Between Exploitative and Interference Competition: Limits to R* Theory

2023

Combatting SARS-CoV-2 With Digital Contact Tracing and Notification: Navigating Six Points of Failure

2023