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Picture of Juanita Merchant

Juanita Merchant

Regents Professor | Chief, Division of Gastroenterology | Professor, BIO5 Institute | Member of the Graduate Faculty | Professor, Medicine | Professor, Cancer Biology - GIDP

Collaboration(55)

Timian Godfrey
Kimberly Shea
Melissa Herbst-Kralovetz
Denise Roe
Jefferey Burgess

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Grants(15)

Development of an Advanced Transnasal Endoscope for Improved Early Detection of Gastric Cancer in Underserved Arizona Communities
Active·2024·$11.3K / $225K·
External
Key Personnel (KP)
endoscopy, cancer detection, medical devices, gastric cancer, health disparities
The Role of Hedgehog and Enteric Neural Crest Cell Reprogramming in Neuroendocrine Differentiation
Active·2023·$0 / $211.2K·
External
Key Personnel (KP)
neuroendocrine differentiation, cell reprogramming, hedgehog, enteric neural crest, role
University of Arizona Cancer Center - Cancer Center Support Grant
Active·2022·$11.2M / $12.6M·
External
Principal Investigator (PI)
cancer research, medical oncology, grants, cancer treatment, supportive care
University of Arizona Cancer Center - Cancer Center Support Grant
Active·2022·$0 / $1M·
External
Key Personnel (KP)
cancer research, medical oncology, grants, cancer treatment, supportive care
Reducing Disparities In Esophageal Cancer Screening For Mexican-Hispanic Patients With Targeted Multispectral And Polarization-Sensitive Imaging
Active·2022·$0 / $594K·
External
Key Personnel (KP)
cancer screening, medical imaging, health disparities, mexican-hispanic patients, multispectral imaging

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Publications(148)

Recent

Moving Ua NOTCH: Defining the Stem Cell Niche in the Gastric Antrum

2022

stem cells, gastric antrum, notch signaling, stem cell niche, gastric tissue regeneration

Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids

2021

cancer, immunotherapy, transcriptional regulation, hedgehog pathway, mtor signaling

Genome analysis identifies differences in the transcriptional targets of duodenal versus pancreatic neuroendocrine tumours

2021

genomics, cancer, transcription, neuroendocrine, tumours

Myeloid-derived suppressor cells in gastrointestinal cancers: A systemic review

2021

immunotherapy, gastrointestinal cancer, myeloid-derived suppressor cells, systematic review, oncology

Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids

2021

cancer immunotherapy, her2 inhibition, tumor immune evasion, gastric cancer organoids, tumor microenvironment

Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma.

2020

organoid, immune cell, pancreatic cancer, co-culture, preclinical model

ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway

2020

cancer, stem cells, liver, regulation, signaling pathway

A brief review of liver injury in patients with Corona Virus Disease-19 during the pandemic.

2020

liver injury, coronavirus, pandemic, patients, disease-19

MiR130b from Schlafen4+ MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer.

2020

microrna, gastric cancer, epithelial proliferation, mdscs, pre-neoplastic changes

Interleukin-1β Suppresses Gastrin via Primary Cilia and Induces Antral Hyperplasia

2020

interleukin-1β, gastrin, primary cilia, antral hyperplasia, suppression mechanism