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Profile
Jose Ek Vitorin
Assistant Research Professor, Physiology - (Research Series Track)
Physiology
Full Page
Overview
Research
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Collaboration
(5)
Scott Boitano
Mutual work: 1 Proposal﹒1 Publication
Collaboration Details
Josef Vagner
Mutual work: 1 Publication﹒1 Proposal
Collaboration Details
Mohammad Shahidullah
Mutual work: 6 Proposals﹒2 Grants﹒1 Publication
Collaboration Details
Nicholas Delamere
Mutual work: 2 Grants﹒6 Proposals﹒1 Publication
Collaboration Details
Jordan Lancaster
Mutual work: 1 Publication
Collaboration Details
Grants
(6)
Connexins as Potential Biomarkers and Therapeutic Targets for Vascular Malformation
Active
·
2024
·
$15.3K
·
External
Principal Investigator (PI)
biomarkers,
therapeutic targets,
vascular malformation,
connexins,
research
TRP Channels as Master Controllers of Lens Function
Active
·
2021
·
$161.2K / $1.6M
·
External
Co-Investigator (COI)
ion channels,
ocular function,
biophysics,
cell signaling,
sensory physiology
Hemichannels, TRPV4 and a Mechanosensitive Form of Autocrine Regulation in the NPE
Active
·
2019
·
$110K / $2.2M
·
External
Co-Investigator (COI)
gap junctions,
trpv4,
autocrine regulation,
mechanosensitive channels,
cell signaling
Role of S-nitrosylated Cx43 in Normal Cardiac Contractility
2022
·
$54.4K
·
External
Principal Investigator (PI)
cardiac contraction,
s-nitrosylation,
cx43,
cardiac function,
nitric oxide signaling
Phosphorylation and Gating of Cardiac Connexin Channels
2016
·
$0 / $1.5M
·
External
Co-Investigator (COI)
cardiac connexin channels,
phosphorylation,
gating mechanisms,
cardiac channel regulation,
cellular communication
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Publications
(25)
Recent
The Role of GaJunctions Dysfunction in the Development of Cataracts: From Loss of Cell-to-Cell Transfer to Blurred Vision-Review
2023
cataracts,
cell-to-cell transfer,
gajunctions dysfunction,
development,
vision
Channel Behavior and Voltage Gating of a Cx43 Mutant Simulating Preconditioning
2023
ion channels,
voltage gating,
cell communication,
cardiac health,
molecular biology
Patch clamstudies on TRPV4-dependent hemichannel activation in lens epithelium
2023
ion channels,
epithelial cells,
lens,
cell signaling,
visual system
MicroRNA-mediated downregulation of K channels in pulmonary arterial hypertension
2020
microrna,
pulmonary hypertension,
k channels,
gene regulation,
cardiovascular disease
The lipidated connexin mimetic peptide SRPTEKT-Hdc is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform
2019
peptide inhibitors,
connexin channels,
phospho-isoform specificity,
lipidated peptides,
membrane proteins
Cx43 channel gating and permeation: Differential roles of the carboxyl terminus
2018
gap junctions,
protein channels,
membrane permeation,
ion transport,
molecular interactions
Cx43 Channel Gating and Permeation: Multiple Phosphorylation-Dependent Roles of the Carboxyl Terminus
2018
gap junctions,
phosphorylation,
channel gating,
permeation,
protein regulation
Determinants of Cx43 Channel Gating and Permeation: The Amino Terminus
2016
ion channels,
gap junctions,
cell communication,
protein structure,
membrane transport
An electrically coupled tissue-engineered cardiomyocyte scaffold improves cardiac function in rats with chronic heart failure
2014
tissue engineering,
cardiac regeneration,
chronic heart failure,
regenerative medicine,
electrical stimulation
Structural determinants and proliferative consequences of connexin 37 hemichannel function in insulinoma cells
2014
cell biology,
molecular biology,
medical research,
insulinoma,
connexins