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Picture of Cynthia Miranti

Cynthia Miranti

Professor, Cellular and Molecular Medicine | Interim Department Head, Cellular and Molecular Medicine | Professor, BIO5 Institute | Member of the Graduate Faculty | Chair, Cancer Biology - GIDP

Cellular & Molecular Medicine

Collaboration(28)

Cynthia Thomson
Denise Roe
Rachna Shroff
Benjamin Lee
Megha Padi

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Grants(10)

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Publications(68)

Recent

Microfluidic-based human prostate cancer on chip.

2024

cancer, microfluidics, medical research, biomedical engineering, organ-on-a-chip

AR loss in prostate cancer stroma mediated by NF-κB and p38-MAPK signaling disrupts stromal morphogen production.

2024

prostate cancer, stromal morphogen production, nf-κb signaling, p38-mapk signaling, ar loss

PIM kinases regulate actin dynamics and tumor cell invasion in hypoxia

2023

kinase regulation, actin dynamics, tumor cell invasion, hypoxia response, cancer biology

Building capacity for collaborative research between basic scientists and underrepresented communities in cancer research

2023

cancer research, collaborative research, community engagement, capacity building, basic science

PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion

2023

cancer, cell biology, protein kinases, tumor invasion, actin dynamics

Direct phosphorylation and stabilization of HIF-1α by PIM1 kinase drives angiogenesis in solid tumors

2021

cancer, angiogenesis, protein kinase, hif-1α, tumor microenvironment

Targeted Phage Display-based Pulmonary Vaccination in Mice and Non-human Primates

2021

vaccination, phage display, pulmonary delivery, immunization, animal models

Aberrant CREB1 activation in prostate cancer disrupts normal prostate luminal cell differentiation.

2021

prostate cancer, cell differentiation, creb1 activation, luminal cells, aberrant activation

Tetraspanin CD82 is necessary for muscle stem cell activation and supports dystrophic muscle function

2020

muscle stem cells, tetraspanin cd82, dystrophic muscle, cell activation, muscle function

Gene expression analysis of human prostate cell lines with and without tumor metastasis suppressor CD82

2020

gene expression, prostate cancer, metastasis, cell lines, tumor suppressor